Speaker: John Robert Cressman, Ph.D., Associate Professor, Physics, George Mason University
Abstract: Seizures and Migraines share a number of similar physiological features. Perhaps most striking is the prominent role of ionic imbalance in the initiation, and spread of pathological activity within the brain. We have explored these features experimental and computationally in an attempt to understand the hysiological abnormalities that can lead to these conditions. Results suggest that failures in glial and vascular support are likely candidates for poor ionic regulation and are therefore potential targets for treatments. I will conclude with results utilizing focused ultrasound stimulation to modulate the local ionic environment and discuss its potential clinical applications.
Bio: John Robert Cressman’s research has focused on investigating dynamical structures in driven systems with a specific interest in their role in the functions of the brain. Transient but long-lived correlated dynamics underlie innumerable biological processes, from the lifecycle of an organism to conscious thought and social behavior. Transient dynamical structures are also the hallmark of a number of natural phenomena, including tornadoes, hurricanes, gyres, and von Karman vortex streets, simple fluid systems that can support coherent structures.
This event has been rescheduled for May 8, 2020.